Recombinant Human Transaldolase/TALDO1 Protein (His Tag)

Recombinant Human Transaldolase/TALDO1 Protein (His Tag)

SKU #	PKSH033132
Expression Host	HEK293 Cells

Description

Synonyms	TAL,TALDO,TALDO1,TALDOR,Transaldolase
Species	Human
Expression Host	HEK293 Cells
Sequence	Met 1-Lys337
Accession	P37837
Calculated Molecular Weight	38.6 kDa
Observed Molecular Weight	38 kDa
Tag	C-His
Bio-activity	Not validated for activity

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin	< 1.0 EU per g of the protein as determined by the LAL method.
Storage	Store at < -20C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20C.
Formulation	Supplied as a 0.2 m filtered solution of 20mM Tris-HCl, 10% Glycerol, pH 8.0.
Reconstitution	Not Applicable

Background
Transaldolase (TALDO1) belongs to the transaldolase family of Type 1 subfamily. TALDO1 is expressed selectively in oligodendrocytes of the brain. TALDO1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. TALDO1 deficiency results in telangiectases of the skin, hepatosplenomegaly and enlarged clitoris.